Research

Main Content

2018

  • Aberdein N, Dambrino RJ, do Carmo JM, Wang Z, Mitchell LE, Drummond HA, Hall JE. Role of PTP1B in POMC neurons during chronic high fat diet: Sex differences in regulation of liver lipids and glucose tolerance. Am J Physiol Regul Integr Comp Physiol. 2018; 314: R478-R488. PMCID: PMC5899251.
  • Adeosun SO, Gordon DM, Weeks MF, Moore KH, Hall JE, Hinds TD, Stec DE. Loss of biliverdin reductase-A (BVRA) promotes lipid accumulation and lipotoxicity in mouse proximal tubule cells. Am J Physiol Regul Integr Comp Physiol. 2018; Apr 4. doi: 10.1152/ajprenal.00495.2017. [Epub ahead of print]. PMID: 29631357.
  • Adeosun SO, Moore KH, Lang DM, Nwaneri AC, Hinds TD, Stec DE. A novel fluorescence-based assay for the measurement of biliverdin reductase activity. React Oxyg Species (Apex). 2018;5(13):35-45. PMCID: PMC5785779.
  • Bakrania BA, Spradley FT, Satchell SC, Stec DE, Rimoldi JM, Gadepalli RSV, Granger JP. Heme oxygenase-1 is a potent inhibitor of placental ischemia-mediated endothelin-1 production in cultured human glomerular endothelial cells. Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R427-R432. PMCID: PMC5899255.
  • Brooks HL, Lindsey ML. Guidelines for authors and reviewers on antibody use in physiology studies. . 2018 Apr 1;314(4):H724-H732. PMCID: PMC6048465.
  • Bulmer AC, Bakrania BA, Du Toit EF, Boon AC, Clark PJ, Powell LW, Wagner KH, Headrick JP. Bilirubin acts as a multi-potent guardian of cardiovascular integrity: More than just a radical idea. . 2018 Sep 1;315(3):H429-H447. PMID: 29600900.
  • Cates C, Rousselle T, Wang J, Quan N, Wang L, Chen X, Yang L, Rezaie AR, Li J. Activated protein C protects against pressure overload-induced hypertrophy through AMPK signaling. Biochem Biophys Res Commun. 2018 Jan 22;495(4):2584-2594. PMCID: PMC5762421.
  • Chade AR, Williams ML, Engel JE, Guise E, Harvey TW. A Translational Model of Chronic Kidney Disease in Swine. . Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F364-F373.
  • Chade AR, Williams ML, Guise E, Vincent LJ, Harvey TW, Kuna M, Mahdi F, Bidwell GL. Systemic biopolymer-delivered vascular endothelial growth factor promotes therapeutic angiogenesis in experimental renovascular disease. . 2018 Apr;93(4):842-854. PMCID: PMC5866753.
  • Chade AR. Understanding and managing atherosclerotic renovascular disease: Still a work in progress. F1000Res. 2018 Nov 29;7. pii: F1000 Faculty Rev-1862. 
  • Chatterjee R, Davenport CA, Raffield LM, Maruthur N, Lange L, Selvin E, Butler K, Yeh HC, Wilson JG, Correa A, Edelman D, Hauser E. KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts. PLoS One. 2018 Aug 31;13(8):e0203213.
  • Chen X, Li X, Zhang W, He J, Xu B, Wang Z, Cates C, Rousselle T, Li J. Activation of AMPK inhibits inflammatory response during hypoxia and reoxygenation through modulating JNK-mediated NF-κB pathway. . 2018 Jun;83:256-270. PMCID: PMC5960613.
  • Clayton AM, Shao Q, Paauw ND, Giambrone AB, Granger JP, Warrington JP. Postpartum Increases in Cerebral Edema and Inflammation in Response to Placental Ischemia during Pregnancy. . 2018 May;70:376-389. PMCID: PMC5953832.
  • Clemmer JS, Pruett WA, Hester RL, Iliescu R, Lohmeier TE. Role of the heart in blood pressure lowering during chronic baroreflex activation: Insight from an in silico analysis. . 2018 Jul 13. PMID: 30004810. 
  • Clemmer JS, Hester RL, Pruett WA. Simulating a virtual population's sensitivity to salt and uninephrectomy. Interface Focus. 2018 Feb 6;8(1):20160134. PMCID: PMC5740217.
  • Coolen LM, et al. The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond": Unresolved questions, challenges and future directions for the field. . 2018 Apr 14:e12600. PMCID: PMC6461527.
  • da Silva AA, Freeman JN, Hall JE, do Carmo JM. Control of appetite, blood glucose and blood pressure during chronic melanocortin-4 receptor activation in normoglycemic and diabetic NPY deficient mice. Am J Physiol Regul Integr Comp Physiol. 2018; 314: R533-R539. PMCID: PMC5966815.
  • DeLeon-Pennell KY, Iyer RP, Ma Y, Yabluchanskiy A, Zamilpa R, Chiao YA, Cannon PL, Cates C, Flynn ER, Halade G, and Lindsey ML. The Mouse Heart Attack Research Tool (mHART) 1.0 Database. . 2018 Sep 1;315(3):H522-H530. PMCID: PMC6172643.
  • DeLeon-Pennell KY, Mouton AJ, Ero OK, Ma Y, Iyer RP, Flynn ER, Espinoza I, Musani SK, Vasan RS, Hall ME, Fox ER, Lindsey ML. LXR/RXR signaling and neutrophil phenotype following myocardial infarction classify sex differences in remodeling. . 2018 Aug 21;113(5):40. PMCID: PMC6105266.
  • do Carmo JM, da Silva AA, Freeman JN, Wang Z, Moak S, Stec DE, Hall JE. Neuronal Suppressor of Cytokine Signaling 3: Role in Modulating Chronic Metabolic and Cardiovascular Effects of Leptin. Hypertension. 2018; 71: 1248-1257. PMCID: PMC5945310.
  • do Carmo JM, da Silva AA, Moak SP, Browning J, Dai X, Hall JE. Increased sleep time and reduced energy expenditure contribute to obesity after ovariectomy and high fat diet. . 2018 Sep 28. pii: S0024-3205(18)30586-1. PMID: 30273560.
  • Eddy AC, Gene L Bidwell III, and Eric M George. Pro-Angiogenic Therapeutics for Preeclampsia. Biol Sex Differ. 2018 Aug 25;9(1):36
  • Edwards KS, Ashraf S, Lomax TM, Wiseman JM, Hall ME, Gava FN, Hall JE, Hosler JP, Harmancey R. Uncoupling protein 3 deficiency impairs myocardial fatty acid oxidation and contractile recovery following ischemia/reperfusion. Basic Res Cardiol. 2018 Oct 29;113(6):47.
  • Granger JP, Spradley FT, Bakrania BA. The endothelin system: A critical player in the pathophysiology of preeclampsia. . 2018 Apr 10;20(4):32. PMCID: PMC6064647.
  • Guise E and Chade AR. VEGF therapy for the kidney: emerging strategies? Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F747-F751
  • Hall ME, Jordan JH, Juncos LA, Hundley WG, Hall JE. Bold magnetic resonance image in nephrology. Int J Nephrol Renovasc Dis. 2018; 11: 103-112. PMCID: PMC5856054.
  • Hall ME, Wang Z, do Carmo J, Kamimura D and Hall JE. Obesity and metabolic syndrome hypertension. In: Disorders of Blood Pressure Regulation: Phenotypes, Mechanisms, Therapeutic Options, Eds. AE Berbari, G Mancia. Springer Publishing. 2018; 705-722.
  • Hamoud AR, Weaver L, Stec DE, Hinds TD. Bilirubin in the liver-gut signaling axis. Trends Endocrinol Metab. 2018 Mar;29(3):140-150. PMCID: PMC5831340.
  • Hamza SM, Hall JE. Novel approach for simultaneously recording renal sympathetic activity and blood pressure with intravenous infusion in conscious, unrestrained mice. J Vis Exp. 2018; 132: e54120, doi:10.3791/54120. PMID: 29553542.
  • Hinds TD, Jr. and Stec DE. Bilirubin, a Cardiometabolic Signaling Molecule. Hypertension. 2018 Oct;72(4):788-795. PMC6205727. 
  • Horvath S, Oshima J, Martin GM, Lu AT, Quach A, Cohen H, Felton S, Matsuyama M, Lowe D, Kabacik S, Wilson JG, Reiner AP, Maierhofer A, Flunkert J, Aviv A, Hou L, Baccarelli AA, Li Y, Stewart JD, Whitsel EA, Ferrucci L, Matsuyama S, Raj K. Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies. Aging (Albany NY). 2018 Jul 26;10(7):1758-1775.
  • Johnson DA, Guo N, Rueschman M, Wang R, Wilson JG, Redline S. Prevalence and correlates of obstructive sleep apnea among African Americans: the Jackson Heart Sleep Study. Sleep. 2018 Oct 1;41(10).
  • Jones DW, Luft FC, Whelton PK, Alderman MH, Hall JE, Peterson ED, Califf RM, McCarron DA. Can we end the “salt wars” with a randomized clinical trial in a controlled environment? Hypertension. 2018; May 7. pii: HYPERTENSIONAHA.118.11103. doi: 10.1161/HYPERTENSIONAHA.118.11103. PMCID: PMC6002917. [Epub ahead of print]
  • Kamimura D, Suzuki T, Wang W, deShazo M, Hall JE, Winniford MD, Mosley TH, Butler KR, Hall JE. Higher plasma leptin levels are associated with reduced left ventricular mass and left ventricular diastolic stiffness in black women: Insights from the Genetic Epidemiology Network of Arteriopathy (GENOA) study. . 2018 Jun 15. PMID: 29907861. [Epub ahead of print]
  • Kuna M, Mahdi F, Chade AR, Bidwell GL. Molecular Size Modulates Pharmacokinetics, Biodistribution, and Renal Deposition of the Drug Delivery Biopolymer Elastin-like Polypeptide. . 2018 May 21;8(1):7923. PMCID: PMC5962569.
  • Li X, Rout P, Pan L, Ma Y, Tchounwou P, Lui Y. Quantification of MicroRNAs by Coupling Cyclic Enzymatic Amplification with Microfluidic Voltage-Assisted Liquid Desorption Electrospray Ionization Mass Sprctrometry. . 2018 Nov 20;90(22):13663-13669. PMCID: PMC6311092.
  • Lin X, Chan KK, Huang YT, Luo XI, Liang L, Wilson J, Correa A, Levy D, Liu S. Genetic Determinants for Leisure-Time Physical Activity. Med Sci Sports Exerc. 2018 Aug;50(8):1620-1628
  • Lindsey ML. Assigning matrix metalloproteinase roles in ischaemic cardiac remodeling. . 2018 Aug;15(8):471-479. PMCID: PMC6203614.
  • Lindsey ML. Regulating macrophage infiltration to alter wound healing following myocardial infarction. . 2018 Oct 1;114(12):1571-1572. PMCID: PMC6148456.
  • Lindsey ML, Eisner DA. Editorial Review: Cardiac Physiology from inside to out. Current Opinion in Physiology. 2018 Feb;1:4-7.
  • Lindsey ML, et al. Guidelines for experimental models of myocardial ischemia and infarction. . 2018 Apr 1;314(4):H812-H838. PMCID: PMC5966768.
  • Lindsey ML, Jung M, Hall ME, DeLeon-Pennell KY. Proteomic analysis of the cardiac extracellular matrix: clinical research applications. Expert Rev Proteomics. 2018 Feb;15(2):105-112. PMCID: PMC5846092.
  • Lindsey ML, Kassiri Z, Virag JAI, de Castro Bras LE, Scherrer-Crosbie M. Guidelines for measuring cardiac physiology in mice. . 2018 Apr 1;314(4):H733-H752. PMCID: PMC5966769.
  • Lindsey ML, Ma Y, Flynn ER, Winniford MD, Hall ME, DeLeon-Pennell KY. Identifying the molecular and cellular signature of cardiac dilation following myocardial infarction. Biochim Biophys Acta Mol Basis Dis. 2019 Jul 1;1865(7):1845-1852. doi: 10.1016/j.bbadis.2018.09.023. Epub 2018 Sep 20.PMID: 31109452
  • Lindsey ML, Mouton AJ, Ma Y. Adding Reg3β to the acute coronary syndrome prognostic marker list. . 2018 May 1;258:24-25. PMID: 29544938.
  • Loria AS, Spradley FT, Obi IE, Becker BK, De Miguel C, Speed JS, Pollock DM, Pollock JS. Maternal separation enhances anticontractile perivascular adipose tissue function in male rats on a high-fat diet. Am J Physiol Regul Integr Comp Physiol. 2018 Dec 1;315(6):R1085-R1095. doi: 10.1152/ajpregu.00197.2018.
  • Ma Y, Moulton AJ, Lindsey ML. Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction. Transl Res. 2018 Jan;191:15-28. PMCID: PMC5846093.
  • Meschiari CA, Jung M. Iyer RP, Yabluchanskiy A, Toba H, Garrett MR, Lindsey ML. Macrophage overexpression of matrix metalloproteinase-9 in aged mice improves diastolic physiology and cardiac wound healing after myocardial infarction. Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H224-H235. PMCID: PMC5867652.
  • Moore AM, Lucas KA, Goodman RL, Coolen LM, Lehman MN. Three dimensional imaging of KNDy neurons in the mammalian brain using optical tissue clearing and multiple label immunocytochemistry. . 2018 Feb 2;8(1):2242. PMCID: PMC5797235.
  • Mouton AJ, DeLeon-Pennell KY, Rivera Gonzalez OJ, Flynn ER, Freeman TC, Saucerman JJ, Garrett MR, Ma Y, Harmancey R, and Lindsey ML. Mapping macrophage polarization over the myocardial infarction time continuum. . 2018 Jun 4;113(4):26. PMCID: PMC5986831.
  • Mouton AJ, Rivera Gonzalez OJ, Kaminski AR, Moore ET, Lindsey ML. Matrix metalloproteinase-12 as an endogenous resolution promoting factor following myocardial infarction. . 2018 Nov;137:252-258. PMCID: PMC6239213.
  • Mouton AJ, Rivera Gonzalez OJ, Lindsey ML. Myocardial Infarction Remodeling that Progresses to Heart Failure: A Signaling Misunderstanding. . 2018 Jul 1;315(1):H71-H79. PMCID: PMC6087773. 
  • Ninh VK, El Hajj EE, Mouton AJ, El Hajj MC, Gilpin NW, Gardner JD. Chronic Ethanol Administration Prevents Compensatory Cardiac Hypertrophy in Pressure Overload. . 2018 May 30. PMCID: PMC6269226.
  • Ojeda NB, Alexander BT. Ex Utero Renal Maturation and Reduced Kidney Volume; A Predictor of Increased CardioRenal Risk. Hypertension. 2018 Oct;72(4):832-833. 
  • O'Reilly J, Lindsey M:, Baugh JA. Physiological proteomics of heart failure. Curr Opin Physiol. Elsevier. 2018 Feb;1:185-197.
  • Quan N, Wang L, Chen X, Luckett C, Cates C, Rousselle T, Zheng Y, Li J. Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway. J Mol Cell Cardiol. 2018 Feb;115:170-178. PMCID: PMC5820139.
  • Reckelhoff JF, Alexander BT. Reproducibility in animal models of hypertension: a difficult problem. Biol Sex Differ 2018 Dec 22;9(1):53.
  • Rodriguez R, Lee A, Mathis KW, Broome HJ, Thorwald M, Martinez B, Nakano D, Nishiyama A, Ryan MJ, Ortiz RM. Angiotensin receptor and tumor necrosis factor-α activation contributes to glucose intolerance independent of systolic blood pressure in obese rats. . 2018 Oct 1;315(4):F1081-F1090. PMID: 29993275. 
  • Sims CR, Delima LR, Calimaran A, Hester R, Pruett WA. Validating the Physiologic Model HumMod as a Substitute for Clinical Trials Involving AcuteNormovolemic Hemodilution. Anesth Analg. 2018 Jan;126(1):93-101. PMID: 28863020.
  • Spann RA, Lawson WJ, Bidwell GL 3rd, Zamarripa CA, Maranon RO, Bandyopadhyay S, Taylor EB,
    Reckelhoff JF, Garrett MR, Grayson BE. Rodent Vertical Sleeve Gastrectomy Alters Maternal Immune Health and Feto-placental Development. . 2018 Jan 25;132(2):295 312. PMCID: PMC5989318. 
  • Speed JS, Hyndman KA, Roth KJ, Heimlich JB, Kasztan M, Fox BM, Johnston JG, Becker BK, Jin C, Gamble KL, Young ME, Pollock JS, Pollock DM. High dietary sodium causes dyssynchrony of the renal molecular clock in rats. . 2018 Jan 1;314(1):F89-F98. PMCID: PMC5866350.
  • Spradley F, Smith J, Alexander BT, Anderson C. Developmental origins of non-alcoholic fatty liver disease as a risk factor for exaggerated metabolic and cardiovascular-renal disease. . 2018 Mar 6. PMID: 29509436.
  • Spradley FT, Ge Y, Haynes BP, Granger JP, Anderson CD. Adrenergic receptor blockade attenuates placental ischemia-induced hypertension. Physiol Rep. 2018 Sep;6(17):e13814. doi: 10.14814/phy2.13814.
  • Sundararaghavan VL, Binepal S, Stec DE, Sindhwani P, Hinds TD Jr. Bilirubin, a new therapeutic for kidney transplant? . 2018 Oct;32(4):234-240. PMID: 29983261. 
  • Syed M, Ball JP, Mathis KW, Hall ME, Ryan MJ, Rothenberg ME, Yanes Cardozo LL, Romero DG. MicroRNA-21 ablation exacerbates aldosterone-mediated cardiac injury, remodeling, and dysfunction. Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1154-E1167
  • Taylor EB, Barati MT, Powell DW, Turbeville HR, Ryan MJ. Plasma Cell Depletion Attenuates Hypertension in an Experimental Model of Autoimmune Disease. Hypertension. 2018 Apr;71(4):719-728. PMCID: PMC5843526.
  • Tudorancea I, Lohmeier TE, Alexander BT, Pieptu D, Serban DN, Iliescu R. Reduced Renal Mass, Salt Sensitive Hypertension Is Resistant to Renal Denervation. . 2018 Apr 30;9:455. PMCID: PMC5936777. [Epub ahead of print]
  • Wang L, Quan N, Sun W, Chen X, Cates C, Rousselle T, Zhou X, Zhao X, Li J. Cardiomyocyte specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury. . 2018 May 1;114(6):805-821. PMCID: PMC5909650.
  • Weaver L, Hamoud AR, Stec DE, Hinds TD Jr. Biliverdin Reductase and Bilirubin in Hepatic Disease. . 2018 Jun 1;314(6):G668-G676. PMCID: PMC6032063. 
  • Wilson JG, et al. Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease. . 2018 Mar 28;14(3):e1007293. PMCID: PMC5891078.
  • Wilson JG, et al. Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nat Commun. 2018 Aug 23;9(1):3391. doi: 10.1038/s41467-018-05747-8. 
  • Wilson JG, et al. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018 Jul 4;9(1):2606. doi: 10.1038/s41467-018-04668-w. 
  • Wilson JG,. Deletion of the Duffy antigen receptor for chemokines (DARC) promotes insulin resistance and adipose tissue inflammation during high fat feeding. . 2018 Sep 15;473:79-88. PMCID: PMC6045443. 
  • Wilson JG, et al. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. . 2018 Jan 9;115(2):379-384. PMCID: PMC5777025.
  • Wilson JG, et al. Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biol. 2018 Jul 17;19(1):87.
  • Wilson JG, et al. Genetic and Environmental Effects on Gene Expression Signatures of Blood Pressure: A Transcriptome-Wide Twin Study. . 2018 Mar;71(3):457-464. PMCID: PMC5877117.
  • Wilson JG, et al. Genome-wide association study of homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults study. . 2018 Mar;63(3):327-337. PMCID: PMC5826839. 
  • Wilson JG, et al. Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans. Genet Epidemiol. 2018 Sep;42(6):559-570.
  • Wilson JG, et al. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nat Commun. 2018 Dec 3;9(1):5141.
  • Wilson JG, et al. Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling. . 2018 Jan 16;137(3):222-232. PMCID: PMC5771958.
  • Wilson JG, et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. . 2019 Jul;51(7):1191-1192. PMID: 31160809.
  • Wilson JG, et al. Transethnic Evaluation Identifies Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations. . 2018 Apr 1;103(4):1380-1392. PMCID: PMC6276579.
  • Wilson JG, et al. West Nile ancestry and nocturnal blood pressure in African Americans: the Jackson Heart Study. . 2018 May 7;31(6):706-714. PMCID: PMC5946866.
  • Wilson JG, et al. Whole genome sequence analyses of brain imaging measures in the Framingham Study. . 2018 Jan 16;90(3):e188-e196. PMCID: PMC5772158.
  • Zhang Q, Ding Y, He K, Li H, Gao F, Moehling T, Wu X, Duncan J, Niu Q. Exposure to alumina nanoparticles in female mice during pregnancy induces neurodevelopmental toxicity in the offspring. . 2018 Mar 20;9:253. PMCID: PMC5869208.